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Long COVID Study

Do you have post-COVID brain fog? 

You may be eligible for a clinical trial testing a drug for post-COVID-19 cognitive impairment if you: 

  • Are 18+ years old

  • Have a previous COVID-19 infection

  • Have been experiencing mental slowness since COVID-19 infection 

  • Are a resident of Canada

Find out more below!

Study Information

What is Long COVID: 

Approximately 1/5 individuals diagnosed with COVID-19 experience persistent cognitive difficulties (including problems with memory, concentration, and mental fatigue) after they have recovered from the acute phase of their illness. These cognitive difficulties are one symptom of ‘Long COVID’, which is a syndrome composed of multiple persistent symptoms including, but not limited to, difficulty breathing, lack of smell or taste, headache, and muscle or joint pains.  


What is the purpose of the Long COVID study?

The Long COVID study will help determine if an approved medication is effective in people suffering from lingering brain fog from their prior COVID-19 infection. 


Is the study drug Safe? 

The study drug is a prescription drug that is approved by Health Canada and FDA-approved for use in patients with depression. The FDA also recognizes pro-cognitive effects of the study drug in persons with depression. The most common side effect is nausea, which normally subsides after a few days.


What should I know about this study? 

If you are experiencing cognitive difficulties (e.g. problems with concentration, memory, and mental fatigue) that started or worsened after you were infected with COVID-19, you are invited to participate in this study. The study team will ask you some quick questions over the phone to see if you are eligible to participate and answer any further questions you may have. If you are eligible, you will be randomly assigned to receive either the study drug or placebo (e.g., sugar pill) once a day for 8 weeks. Neither you nor the study team members will know what you are getting until the study is complete. 


During this 8-week period, your cognitive and mood symptoms will be monitored regularly. You will also be seen by a physician on the study team to see how you are doing at every visit. You will also be asked to provide a fasting blood sample at the start and end of the study. Lastly, you may be asked about your interests to voluntarily  participate in an optional fMRI scan of your brain before and after the study. For more details about the study plan, please see the table below. 

Which organization is running this study? 

The Brain and Cognition Discovery Foundation (BCDF) is a registered non-profit organization with a focus on research and education in the areas of brain health and disease. Please visit for more information about BCDF. 


Will compensation be provided?

You will receive a modest stipend for your time. 

Study Visits


Criteria for Participation

  • Age 18+

  • Have a previous COVID-19 infection

  • Have been experiencing mental slowness since COVID-19 infection

  • Resident of Canada

Our Team

In the News

I have more questions/How can I participate?

Please call 647-450-8045 or email to speak to a member of the research team and find out more information. 

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